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These investigations reveal that IGF-1 facilitates tendon regenerative healing through multiple pathways, including modulation of inflammatory responses, promotion of cell proliferation and migration, enhancement of collagen production, and induction of cell differentiation (Figure 3)

Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, Mann JF, Nauck MA, et.al

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Regarding LA and LV dilation criteria, there is now scientific evidence that the proposed multibreed echocardiographic ACVIM cut-offs do not perfectly fit for several specific breeds, and the use of breed-specific reference intervals would be more appropriate

scale bar, 50 m