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In elderly individuals, lower serum 25(OH)D levels are correlated with elevated C-reactive protein (CRP) and systemic inflammation, while VDR dysfunction is associated with impaired bone metabolism and aging-related phenotypes [77, 78]

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Ultrastructural pathology and restoration in PFC and hippocampal CA1 neurons Transmission electron microscopy (TEM) analysis of prefrontal cortex (PFC) and hippocampal CA1 neurons revealed significant ultrastructural alterations across experimental groups

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GSH, an endogenous low-molecular-weight thiol-containing compound, plays an essential role in cellular redox reactions and protects cells from ROS 37