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Response: We appreciate the applicant's clarification and the commenters' input

That actually goes against the Hippocratic oath, which is do no harm and if we dont know if were causing harm, thats an issue.

Over time, they can release inflammatory signals (often called the SASP, or senescence-associated secretory phenotype) that may contribute to tissue dysfunction seen with aging and some age-related conditions

Very low blood sugar (hypoglycemia) can be dangerous

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