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Many participants in the trial reported gastrointestinal issues, such as nausea and vomiting, when taking the medication
Official Injection Sites for GLP-1 Medications According to their FDA-approved prescribing information, GLP-1 medications semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound) are administered as injections just under the skin (subcutaneous) in three areas: Abdomen avoid the 2 inches (5 cm) directly around the navel Thigh outer/front thigh Upper arm back of the upper arm All four FDA labels (Ozempic 1 , Zepbound 2 , Mounjaro 3 , Wegovy 4 ) explicitly state that patients should rotate injection sites with each dose
It mimics a naturally occurring hormone (GLP-1) that regulates appetite and blood sugar
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The upper arm The back of the upper arm works well but presents a practical challenge: most people cannot comfortably self-inject in that location
