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So entsteht ein geschlossener Kreislauf: Aufnahme, Eigenproduktion, Erneuerung

doi: 10.18632/oncotarget.10591 359 YuK.TenagliaV.ChuaE

This upregulation of IGF-1 may potentially initiate a signaling cascade involving the activation of phosphoinositide 3-kinase (PI3K), an enzyme that may phosphorylate and activate protein kinase B (Akt)

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