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Phospholipid peroxy radicals are relatively unstable and can react with Fe 2+ , resulting in a chain expansion of phospholipid peroxidation, thus triggering ferroptosis signals (31, 32)

Focus on areas that need extra attention, like dry patches or areas prone to breakouts

Researchers must navigate these requirements while maintaining scientific rigor and participant safety

If you plan to resume, restart at the full dose rather than titrating back up, since the break period allows receptor resensitization

After the reaction, the solvent was removed by rotary evaporation, and then washed three times with ethyl acetate to obtain compound a, which was directly used in the next step without purification