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There were inhibited mRNA of inflammatory mediators (iNOS, IL-6, IFN and TNF-), increased expression of HSP 70 and 90, and antioxidant proteins, such as HO-1, NQO-1, glutathione reductase, glutathione peroxidase 2 and GST-pi [30]

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Treatment duration and follow-up ranged between three and four months

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Dose Range: 2.515 mg weekly with 4week titration intervals

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