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The animals were placed in the stereotaxic device (David Kopf Instruments, Tujunga, CA, USA) and holes were drilled in the frontal, parietal, and occipital regions of the skull at the following locations: 2 mm from Bregma, 2 mm lateral to the midline (ipsilateral), and 2 mm posterior to Lambda (reference electrode)
Translation beyond that controlled model is unestablished
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Oral glutathione supplements have historically shown poor bioavailability, meaning much of the ingested glutathione is broken down in the digestive system before reaching the bloodstream
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