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Description

The rise of the ATP:ADP ratio in the cytoplasm closes the plasmalemmal ATP-sensitive potassium channel (K ATP ), resulting in depolarisation of the plasma membrane, which triggers the opening of the voltage-gated Ca 2+ channel [5]

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Under these conditions, epithelioids maintained a stable morphology with a basal layer of TRP63 + epithelial progenitor cells 43 , and expressed the hemidesmosome protein ITGA6 exclusively on the basal aspect of the cell membrane as in vivo 33

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