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Evaluate the OSA pathway specifically the pharmacy benefit rules for the OSA indication may differ from the weight management pathway

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The specific J-code depends on the drug administered

The beneficial effect of tirzepatide on hsCRP, a biomarker of systemic inflammation, YKL-40, a proinflammatory cytokine, and ICAM-1, a biomarker of endothelial dysfunction, was already detectable at 4 weeks, consistent with the salutary effects of GIP and GLP-1 on inflammation and atherosclerosis in experimental models [84,85,86]

Regulatory decisions like this signal a shift toward broader, more inclusive care