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Conversely, TGF-RI upregulation exacerbates MASLD and fibrosis, as seen in models of SIX1 (Sine oculis homeobox homologue 1) or SHMT2 (Serine hydroxymethyl transferase 2) expression (Gao et al

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However, they dose not substantially alter long-term eGFR trajectories [65]

Dose-response assays (30 pM - 1 M) were performed in duplicate with Ex-4 as a positive control

Assembling the Syringe: Most syringes are single use pre-assembled