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Warnings and Precautions 5.1 Risk of Thyroid C-Cell Tumors In mice and rats, semaglutide caused a dose-dependent and treatment-duration-dependent increase in the incidence of thyroid C-cell tumors (adenomas and carcinomas) after lifetime exposure at clinically relevant plasma exposures [see Nonclinical Toxicology (13.1)]

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This research was funded by the Fundamental Research Business Expenses of the Central Universities, grant number 2024GCZX002

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