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Digestive Effects That May Influence Sleep Semaglutide slows digestion, which can sometimes cause: Nausea Bloating Stomach discomfort If these symptoms occur near bedtime, they may temporarily interfere with falling asleep or staying asleep

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But theres a catch: Because these medications reduce appetite so effectively, people often: Eat much less overall Miss out on protein and fiber Lose muscle mass along with fat A recent JAMA Internal Medicine patient guide emphasizes that people on GLP-1 medications commonly lose both fat and lean mass, and may experience GI symptoms that make eating harder

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