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10-O-(N, N-dimethylaminoethyl) ginkgolide B methanesulfonate (XQ-1H) has been shown to normalize the expression of claudin-5, occludin, ZO-1, and -catenin in ischemic stroke model mice, leading to reduced BBB permeability and protection against oxygenglucose deprivation/reoxygenation injuries [292]

5,10-methyleneTHF acts as the cofactor in both the de novo thymidylate and homocysteine remethylation pathways in the nucleus and cytoplasm respectively

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