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The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity

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International journal of food sciences and nutrition

In another double-blind, placebo-controlled trial, an improvement in cognitive performance (i.e., MMSE score) was reported in AD patients randomized to receive 800 IU/day of all - rac --tocopherol (360 mg/day of RRR --tocopherol) for six months only when the treatment effectively reduced oxidative stress (as assessed by the measure of total glutathione and markers of lipid peroxidation in the blood) (110)

Aitken RJ, Gordon E, Harkiss D, Twigg JP, Milne P, Jennings Z, Irvine DS: Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa