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The short version: GLP-1 reduces how much you eat

And we decide which one is right for a specific patient looking at other health conditions like, does my patient have heart disease or kidney problems, diabetes

Thats not a reason to panic, but it is a reason for appropriate humility about what we can confidently claim

The chemical structure was first described 20 years later, and it was in the 1970s that L-carnitine deficiencies were first discovered in humans [15]

However, as discussed next, a bona fide indication for GLP-1 RAs to reduce the risk of developing HF or to treat chronic HF arguably requires the resolution of several unknowns