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Therapeutic strategies aimed at reducing uremic toxin levels, such as the use of intestinal adsorbents or gut microbiota modulators (e.g., probiotics), may help mitigate macrophage-driven vascular inflammation

Ongoing weight management with GLP-1 maintenance dosing supports long-term metabolic health

By modulating dopamine pathways in the brain, these medications could help reduce cravings and compulsive behaviours across a spectrum of addictions

Melanotan I (also known as afamelanotide) acts on MC1R and has increased resistance to enzymatic breakdown, whereas melanotan II is a shorter cyclic variant that increases pigmentation at a lower cumulative dose and is less specific and more lipophilic, thereby crossing the blood-brain barrier more easily, leading to more widespread adverse effects

These capsules are designed with advanced excipient technology that ensures stable and effective dosing, optimizing each dose