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Broad Therapeutic Effects : Tirzepatide results in clinically significant improvements in multiple obesity-related complications, including sleep apnea, metabolic dysfunction-associated steatohepatitis, heart failure with preserved ejection fraction, and diabetes prevention [79]
Beyond pancreatic effects, GLP-1 slows gastric emptying, which moderates postprandial glucose excursions, and acts on central nervous system receptors to promote satiety and reduce appetite
It is important to be direct about that
2018;20(S2):13744
(This analysis does not include all GLP-1s covered by Medicare, only those products with more recent FDA approvals that are also approved as weight loss medications.) Spending on Ozempic alone increased substantially between 2021 and 2022
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