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Can GLP1s be prescribed to people without diabetes

Independently of the gut effect, GLP-1 receptors in the hypothalamus and brainstem are directly activated by the medication, reducing hunger signaling at the source

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Mainly expressed in the ileum and colon, GLP-1 is known as the most powerful incretin in humans and lowers postprandial blood glucose via augmentation of glucose-dependent insulin release from pancreatic -cells, inhibition of glucagon secretion from pancreatic -cells, and delay of GE