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Acetaldehyde further compromises the ER by modifying chaperones and enzymes, interfering with disulfide bond formation and glycosylation, depleting glutathione, disturbing calcium signaling, and causing homocysteine accumulation ( Alcohol and endogenous aldehydes also cause DNA double-strand breaks and chromosomal rearrangements in hematopoietic stem cells

Tryptophan extends the life of cytochrome p450

Silymarin ameliorates diethylnitrosamineinduced liver fibrosis in Wistar rats

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It helps the brain grow new dendrites and synapses , forming stronger communication networks across regions responsible for memory, focus, and mood regulation