Another described the experience as the "worst customer service" they had ever encountered, noting that email was the only contact method and responses sometimes took several days
Finally, since endogenous GLP-1 is involved in the regulation of energy metabolism both in the periphery as well as in the brain, compounds acting as GLP-1R agonists can also normalize mitochondrial function, which also appears to be repeatedly disrupted in the depressive brain and thus possibly exacerbate neuroprotective effects, e.g
Like Ozempic and the others, its a GLP-1 medication, one that has been shown to lower blood sugar levels and induce weight loss
In the SURPASS-4 trial, adults with T2DM at heightened cardiovascular risk, who were inadequately managed with oral glucose-lowering agents, once-weekly tirzepatide (5 mg, 10 mg, or 15 mg) were compared to insulin glargine (100 U/mL)
In addition, Semaglutide GLP-1 may have a direct effect on fat cells, promoting the breakdown of cells, particularly when used as part of a comprehensive weight loss program
