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Understanding this connection helps people find real relief rather than treating recurring symptoms

2.7.1 Basic science research The three specific sensor proteins of ER stress are activating transcription factor 6 (ATF6), inositol requiring enzyme 1 (IRE1), and eukaryotic pancreatic ER kinase (PKR)like ER kinase (PERK): each one activates subsets of effector genes comprising ATF4, caspase-12, CHOP, bcl, and NF-B

Yen BL, Yen M-L, Hsu P-J, Liu K-J, Wang C-J, Bai C-H, Sytwu H-K

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Resistance of the normal human microflora to mercury and antimicrobials after exposure to mercury from dental amalgam fillings