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Traditionally, ED management of alcohol-related visits has focused on putting out fires: treating acute intoxication or withdrawal and addressing the immediate threats (trauma, dehydration, electrolyte disturbances)

Supporting glutathione is part of that strategy, particularly for men who are also managing other medications or have elevated liver enzymes at baseline

In WT and KO mice, ALT and AST levels were significantly increased by 4 hours

gallbladder problems - upper stomach pain, fever, clay-colored stools, jaundice (yellowing of the skin or eyes)

In some embodiments, the lipid-based drug delivery formulation or composition comprises a water-soluble preservative wherein the preservative is a benzethonium salt (e.g., benzethonium chloride), benzoic acid, and/or a benzylkonium salt (e.g., benzylkonium chloride)