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This multi-receptor mechanism distinguishes retatrutide from earlier generations of incretin-based research compounds including GLP-1 mono-agonists such as semaglutide, and dual GIP/GLP-1 agonists such as tirzepatide by introducing glucagon receptor activation as an additional metabolic axis

These medications help control blood sugar levels by mimicking the bodys natural GLP-1 hormone, which is released by the small intestine after eating

Back Habener, JF (2024) 'Acknowledgements' 2024 Lasker-DeBaley Clinical Medical Research Award

No tirzepatide, no brand-name path

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