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Cycle regularity and PCOS improvements may partially persist if any weight loss is maintained, but most women regain a significant portion of pre-treatment weight within a year of stopping, per STEP 4 by Rubino et al

There is no established dosing schedule for Reta outside of clinical trials

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While GLP-1s and similar peptides famously suppress appetite, reduce blood sugar, and cause weight loss, a growing body of research suggests they might also do much more: curb inflammation all over your body, increase mitochondria in skeletal muscle to give you more energy and help you build strength, and reduce the risk of conditions ranging from Alzheimers to heart disease to alcohol use disorder