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DSIP, Pinealon, and Epitalon are studied across overlapping laboratory models involving neuropeptide signaling, pineal pathway biology, circadian rhythm systems, CNS response models, oxidative stress biology, and cellular aging pathway research

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Additionally, the activation of microglia and astrocytes in ALS leads to the production of ROS and pro-inflammatory cytokines, further exacerbating oxidative damage and motor neuron degeneration [170]

All the mice (68 weeks) were maintained in a pathogen-free environment with ad libitum access to food and water, and a suitable temperature range of 2025 C and 5065% relative humidity