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Looking at complex 1 in the red box: NADH is oxidised by reducing an oxidised flavin to the fully reduced flavin

Calabrese and his colleagues have also made significant efforts to refine the definition and classification of hormesis: an adaptive response of biological systems to low-intensity stressors, characterized by a biphasic dose-response curve with a stimulatory zone (typically 0.1-10 times the No-Observed-Adverse-Effect Level, NOAEL) and an inhibitory zone 7

J AnimPhysiolAnimNutr (Berl) (2017) 101(4):60528

Researchers investigate these compounds in controlled laboratory settings to better understand peptide behaviour, stability, and other experimental properties