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Metab Brain Dis 30:925933 Deon M, Sitta A, Faverzani JL, Guerreiro GB, Donida B, Marchetti DP, Mescka CP, Ribas GS, Coitinho AS, Wajner M, Vargas CR (2015b) Urinary biomarkers of oxidative stress and plasmatic inflammatory profile in phenylketonuric treated patients

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However, modern research and specialized delivery forms have shown that oral supplementation can indeed support glutathione levels in the body

Given that Glu is primarily neuroactive while Gln is storable and neuroinactive, the Gln/Glu ratio can reflect the efficiency of Glu uptake by astrocytes and its conversion to Gln, which is crucial for regulating excitatory neurotransmission [20]

(4) Associated features: dysmorphisms, developmental delay