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Biochim Biophys Acta 1862(11):20862097 Ouwens DM, Diamant M (2007) Myocardial insulin action and the contribution of insulin resistance to the pathogenesis of diabetic cardiomyopathy

This is especially useful for people following microdosing schedules that do not follow standard escalation patterns

A 2018 randomized controlled trial published in the European Journal of Clinical Nutrition tested this exact regimen in 48 participants consuming five standard drinks over four hours

The addition of glucagon produced approximately 25-30% more weight loss than dual agonism

This study was prior to the use of GLP-1 drugs for obesity, so these findings are applicable to people with diabetes