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"While gastrointestinal side effects like nausea and constipation are common, they are usually temporary and manageable," she notes

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The authors concluded that 82 percent of trials had a study population representative of the sex distribution in the intended patient population, but that minority groups still had lower participation rates than would be representative (with 77 percent of participants white, population average 72 percent) (Eshera et al., 2015)

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When estrogen levels are highparticularly around ovulationthese receptors can become more active, leading to a temporary rise in TSH levels