This research offers further insight into this emerging safety signal, according to the study authors who noted in their Ophthalmology paper, Our novel, stratified analysis provides a more nuanced interpretation than previous pooled reviews, isolating a potential increased risk signal to observational data in the diabetes population only, a finding not corroborated by RCTs. These results are somewhat at odds with the narrative surrounding GLP-1 use and NAION risk that began in early 2024, but the researchers say they are confident in their methodology
Significant associations between Streptococcus , Clostridium , Culturomica , and Bacteroides genera and four NC-CKD-enriched metabolites, including Arachidonic acid, L-Phenylalanine, Dihomogamma-linolenic acid, and N-Acetylputrescine were identified
Product Facts Supplement Facts Serving Size 1 Tablet Servings Per Container 60 Daily Value not established
Janice Thompson and Melinda Manore
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