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Major trends: Expansion of cardiovascular indication labeling to include primary prevention in high-risk patients without established CVD, Growing prescription by cardiologists, expanding the prescriber base beyond endocrinology and primary care, Head-to-head competition with SGLT2 inhibitors for cardiovascular risk reduction, driving comparative effectiveness research, Development of fixed-dose combinations (GLP-1 with SGLT2 inhibitors) to address both glycemic and cardiovascular outcomes, and Integration of GLP-1 therapy into cardiovascular disease management protocols and hospital formularies

Although no subgroup analysis was performed specifically for older adults, changes at the end of 24 weeks were reported to be independent of age [58]

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Because of this lack of data, doctors take a cautious approach

How common is GLP-1 use