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The peptide is constructed on a GIP receptor backbone with non-coded amino acid residues (Aib2, Aib20, aMeL13) and a C20 fatty diacid moiety that enables albumin binding, extending pharmacokinetic half-life for once-weekly administration in research settings

5 Conclusion CHF combining RG showed better therapeutic effects than RG alone, and its renal protective effects were associated with reducing Scr, BUN, UA, and improving eGFR, as well as preventing renal fibrosis

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doi:10.1016/bs.irn.2020.11.004 126

Asthma attacks and experimental antigen challenges are both associated with immediate formation of 22]