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Glutathione serves as an essential cofactor for critical and powerful antioxidant enzymes including superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione reductase (GR) and glutathione-s-transferase (GST)

Metabolomic footprint of disrupted energetics and amino acid metabolism in neurodegenerative diseases: perspectives for early diagnosis and monitoring of therapy

A few years later in childhood (nutritional phase 3), the classical hyperphagia occurs, characterized by constant hunger, lack of satiety, irritability if food is denied, and a range of dysfunctional food-related behaviors, including theft, nighttime eating, and consumption of expired, spoiled or frozen food [27]

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Overexpression of FSP1 effectively inhibited ferroptosis in HT1080 cells but failed to inhibit ferroptosis in COQ2-deficient cells, which indicates that the anti-ferroptosis effect of FSP1 is dependent on CoQ10