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Clinical scenarios where Wegovy might be considered include : Patients with clinically significant weight regain (definitions vary, but often 10-15% from weight nadir) Those with recurrence or worsening of weight-related comorbidities Individuals who have exhausted behavioural and dietary interventions Patients with documented adherence to post-surgical lifestyle recommendations It is essential to recognise that Wegovy is not a substitute for addressing underlying behavioural, psychological, or surgical complications

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The damage can be caused by a broad variety of conditions that compromise the intestinal mucosa, including vascular or hormonal or vasoactive factors or by bacterial endotoxins [1, 4]

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