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The other key indicator of ferroptosis is an increase in the levels of MDA, the final product of lipid oxidation (114)

It is reported that sestrin2 (Sesn2) is a highly evolved, stress-responsive protein essential for oxidative stress resistance

As B12 is essential for the production of red blood cells and proper nervous system function, its deficiency can disrupt these processes and lead to symptoms like gastrointestinal discomfort and poor appetite, which may contribute to unintended weight loss

We acknowledge the Japanese National BioResource Project and the Caenorhabditis Genetics Center, funded by the National Institutes of Health-Officer of Research Infrastructure Programs (P40 OD010440) for providing the C

Phosphorylation of IGF-1R and subsequent activation of downstream signalling cascades were also found to contribute to tamoxifen resistance and drive cell proliferation in breast cancer (Kruger et al., 2020)