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Many patients find it helpful to mark their intended injection quadrants with a washable skin marker or mentally map the rotation sequence before beginning treatment

The trial reached 2 primary endpoints, and the data had statistically significant differences: The main statistical methods showed that in all randomized patients, after 68 weeks of treatment, the SC semaglutide 2.4 mg + IBT treatment group lost 16.0% from the average baseline weight of 105.8 kg, and the placebo + IBT group lost 5.7%

Zehetner explains: These side effects result from delayed gastric emptying and altered intestinal motility triggered by the medications

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