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Therapeutic Doses The difference in dosage is because of different health goals

Linus Pauling Institute Oregon State University Updated in May 2004 by: Jane Higdon, Ph.D

Urology 91:190196

Its proposed mechanisms involve multiple cytoprotective pathways including upregulation of VEGF and growth factors promoting angiogenesis, modulation of the nitric oxide system, activation of the FAK-paxillin pathway for cell migration and tissue repair, interaction with the gut-brain axis affecting dopaminergic and serotonergic systems, and gastroprotective effects against NSAID and alcohol-induced mucosal damage

The National Institutes of Health (NIH) notes that some individuals experience an increased risk of stomach pain if they frequently take acetaminophen-containing cold and flu medications