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In the pre-marketing PIONEER-6 trial, a similar reduction in MACE rates was observed for oral semaglutide versus placebo, though statistical significance was not reached due to smaller event numbers than in SUSTAIN-6 [8]

A study in vitro conducted on a human sebaceous cell line (SZ95) demonstrated the benefits of L-carnitine for oily skin

However, its active ingredient, semaglutide, is also present in Wegovy, the GLP-1 medication FDA-approved for weight loss, and available as a compounded medication

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