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Overall, dysbiosis of the gut microbiota significantly contributes to glucose metabolic abnormalities in PCOS patients by adversely influencing host energy metabolism and promoting chronic inflammation

Though Mounjaro is indicated for diabetes, only around half of new Mounjaro patients have a diabetes diagnosis, while a quarter have a weight-related diagnosis

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MHRA and NICE Guidance: Authorised, With Clear Conditions In November 2023, the MHRA authorised Mounjaro for adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity, such as hypertension or sleep apnoea