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Whether the theory of an underlying proteopathy is correct or not, we would argue that evidence accumulated over the last decade makes this hypothesis a plausible consideration

J Clin Biochem Nutr (2013) 52:916

This fear leads to a rigid adherence to a one-size-fits-all protocol, even when it is not clinically appropriate for the individual

The GstA1 gene, which encodes a 29 kD GST protein (GST29) was specifically inducible by fungal infections and exogenous GSH, but not by various xenobiotics that typically induce GST activity (paraquat, atrazine, alachlor, metolachlor) (Mauch and Dudler, 1993)

Under physiological conditions, p53 acts to sustain the cardiac architecture and adjust the levels of transcripts correlated with metabolism, the cardiac architecture, and excitationcontraction coupling