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Niraparib (MK-4827), a novel poly(ADP-Ribose) polymerase inhibitor, radiosensitizes human lung and breast cancer cells

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Overall, Nrf2 is fundamental for the sustenance of the GSH redox state through glutathione reductase transcriptional regulation and for cell protection against oxidative stress (Harvey et al., 2009)

CS and -actin were used as loading controls

Protein Aggregation Methylene blue prevents misfolded proteins from forming toxic clumps that damage neurons and contribute to disorders like Alzheimer's, potentially slowing neurodegenerative processes