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These overlapped genes which are co-regulated by GSH, Glu, and wounding or independently regulated by GSH and wounding, Glu and wounding are all mainly involved in plant defense signaling, including plant response to wounding, stress, JA, and biotic stimulus, regulation of cell communication, and innate immune response, suggesting that GSH and Glu are involved in wound-induced plant systemic defense response

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In an Italian study, 151 TPO-antibody positive women were randomly assigned to supplementation with 200 g selenium/d (as selenomethionine) or placebo during pregnancy and the postpartum period ( Reference Negro, Greco and Mangieri 97 )