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Matched samples were compared with two-sided Wilcoxon signed-rank test

Overall, HT pathogenesis results from a complex interplay between innate and adaptive immunity, where breakdowns in tolerance, skewed Th1/Th17/Treg balance, and persistent autoantibody production sustain chronic inflammation and irreversible thyroid destruction

Its currently approved by the FDA to treat Barth syndrome, a rare, mitochondrial disease that can lead to an enlarged and weakened heart

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