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Monocytes exhibit altered subset composition, impaired phagocytic capacity, and metabolic reprogramming involving mitochondrial and lysosomal dysfunction, partly linked to mutations in the LRRK2 and GBA1 genes, which further sustain inflammation and alpha-synuclein aggregation

The restoration of its normal level was linked to decreased striatal denervation and DA-ergic neuronal death in toxic-induced mice model of PD (Valds et al., 2014

Detoxification: GSH participates in the detoxification of xenobiotics and endogenous metabolites through conjugation and excretion pathways

10.1155/2021/9221693 Oxid Med Cell Longev