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Nature 585 , 277282 (2020)

The micro-injuries trigger acute inflammation, upregulating TGF- and VEGF pathways for angiogenesis

Regarding treatment strategies, it is suggested that the marked decrease in GPx1 expression may be the major mechanism of tumor sensitization to anthracyclines [93] and that GPx1 can partially inhibit doxorubicin-induced cell death-related signaling in breast cancer by interfering with the activation of the sphingomyelin-ceramide pathway [85]

Because the effect is modest, AOD 9604 tends to be discussed for a specific kind of person rather than as a general weight loss tool