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Some common signs and symptoms include: decreased cognitive function, such as issues with memory or understanding fatigue lethargy constipation feeling faint depression or irritability headache difficulty maintaining balance sore, swollen tongue, which may be pale yellow or very red heart palpitations mouth ulcers paraesthesia (pins and needles) vision changes How Vitamin B12 Deficiency Is Diagnosed The traditional way of diagnosing vitamin B12 deficiency has been with a serum B12 blood test to determine the patients B12 levels as well as the presence of any signs or symptoms of pernicious anaemia

If you have an MTHFR mutation, supplementing with vitamin B12 may be beneficial, as these mutations can impair your body's ability to utilize B12 effectively, potentially leading to deficiency symptoms and elevated homocysteine levels

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After filtering for quality, 36 studies met inclusion criteria for detailed analysis

One study, in particular, suggested that while it could not reverse the effects, a mixture of B12 and Omega-3 could slow down mental decline for early-stage dementia patients