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Related reproductive-biology effects of NNMT inhibition are also under investigation, with some studies noting effects on embryo implantation in models

Chemistry 24 , 22772285 (2018)

Intradiscal injection of SB-01 represents a first-in-class approach to treating chronic discogenic back pain

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Additionally, TF treatment notably decreased the formation of ASC spots, indicating that TF could prevent the assembly of the NLRP3 inflammasome, characterized by the formation of ASC spots and reduced NLRP3 expression (71,72)