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These cell types include intestinal stem cells (ISCs), progenitor cells, transit-amplifying cells (TAs), Paneth cells, enterocyte precursors, enterocytes, BEST4+ enterocytes, goblet cells, enteroendocrine cells (EECs), and tuft cells

Understanding an individual's genetic architecture in these pathways may support more informed medication selection and dose titration, though genetic predisposition does not determine exact treatment outcomes