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Avoid alcohol, as both phentermine and topiramate can amplify its effects and increase the risk of side effects

Targeting Hippo coactivator YAP1 through BET bromodomain inhibition in esophageal adenocarcinoma

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The COVID-19 pandemic has accelerated many of these changes and highlighted the importance of agility, flexibility, and patient-centricity in the clinical trial process

This is mechanistically distinct from the appetite effect and explains why tirzepatide produces greater fat-mass loss relative to lean-mass loss compared to GLP-1 monotherapy in DEXA substudy data from SURPASS-3 [24]